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Treatments counteracting oxidative stress, such as the antioxidant, N-acetylcysteine (NAC), have proven effective in preventing the emergence of behavioural and cognitive disruptions in various models of neurodevelopmental disorders [10, 41,42,43]

Transsulfuration The transsulfurization pathway plays a key role in supplying cysteine for GSH synthesis

Neurochem Res 23:108591, PMID: 9704598 Gilbert KR, Aizenman E, Reynolds IJ (1991) Oxidized glutathione modulates N -methyl-d-aspartate- and depolarization-induced increases in intracellular Ca2+ in cultured rat forebrain neurons

We are now seeing similar effects with high doses of vitamin B-12 ( lung cancer, GI cancers)

Standard Western blotting protocol was performed using fluorescent secondary antibody Goat anti-Rabbit IRDye680 for detection